Recall the different types of feedforward loops. Last lecture we discussed the behavior of the C1 loop. The advantage of the C1 loop is that it protects Z from turning on due to fluctuations in X. This is called a persistence detector.
Now we will examine the behavior of some of the incoherent feedforward loops.
Assume that the signals from X and Y combine in an AND NOT logic fashion to create output Z.
As in the previous lecture, assume that the concentration of X quickly turns on at time .
In summary, there are three ways to speed up response.
- Incoherent feedforward loop
- Increase the degradation rate r and increase the production rate k.
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